Visualization of single-stranded nucleic acid of RNA tumor virus with the electron microscope.
نویسندگان
چکیده
60-70S RNA of avian myeloblastosis virus was spread with the Kleinschmidt method and examined in the electron microscope after being subjected to a variety of denaturing conditions. Extension of the molecules from a collapsed configuration was seen only under stringent denaturing conditions, resulting in molecules of 1-2 mum in length. Longer strands of these extremely fragile molecules cannot be obtained with the methods presently available.
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 71 5 شماره
صفحات -
تاریخ انتشار 1974